The most recent and successful experiences in the application of machine vision-based techniques to structural analysis with main focus on seismic testing by shaking table are described and discussed. In particular, the potentialities provided by 3D motion capture methodologies and, more recently, by motion magnification analysis (MMA) emerged as interesting integrations, if not alternatives, to more conventional and consolidated measurement systems in this field. Some examples of laboratory applications are illustrated with the aim of providing evidence and details on the practical potentialities and limits of these methodologies for vibration motion acquisition, as well as on data processing and analysis.